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MedicaidCoverageMedium impact

25-915 Bill Correctly for HIV Pre-exposure Prophylaxis (PrEP)

Health Net·CA · Family Medicine, Internal Medicine, Infectious Disease +1 more·Prior Authorization
Effective date
Not stated
We identified it
Jun 20, 2026
Days to comply

Summary

Health plans must cover all FDA-approved HIV PrEP medications and integral services without cost sharing, prior authorization, or step therapy (except when therapeutic equivalents exist). Billing teams must use Z29.81 as the primary diagnosis code for all PrEP-related services and follow specific CPT coding guidelines for oral and injectable PrEP protocols.

Action Required

Action needed
Immediately: Billing team must update coding protocols for HIV PrEP services to use Z29.81 as primary diagnosis code for all PrEP-related encounters. Create billing guidelines distinguishing between daily oral PrEP and long-acting injectable PrEP frequency requirements. Train staff on proper CPT code selection based on patient demographics and risk categories. Verify billing system removes prior authorization requirements for FDA-approved PrEP medications unless therapeutic equivalents exist.

Affected Billing Codes

Z29.81
99401
99402
99403
99404
99411
99412
99384
99385
99386
99387
99394
99395
99396
99397
86689
86701
86702
86703
87389
87390
87391
87534
87535
87536
87806
86704
86705
86706
87340
87341
87467
90743
90746
90471
90472
86803
86804
82565
82570
82575
87590
87591
87592
87850
86631
86632
87110
87270
87320
87490
87491
87810
86592
86593
86780
80061
81025
84702
84703
80081
G0432
G0433
G0435
G0475
G0011
G0012
G0013
J0750
J0751
J0799
J0739
96372