Effective October 1, 2026, UnitedHealthcare will require prior authorization for HCPCS code J2860 (siltuximab injection) when administered in outpatient settings for cancer treatment. This applies to all UnitedHealthcare plan types including commercial, Medicare Advantage, Medicaid, and Exchange plans.
Action Required
Before Oct 1, 2026
Before October 1, 2026: Billing team must update system to require prior authorization for HCPCS J2860 (siltuximab injection) for all UnitedHealthcare plans when used for cancer treatment in outpatient settings. Contact oncology prior authorization support at 888-397-8129 or email unitedoncology@uhc.com for questions. Claims submitted without prior authorization will be denied.